the action of some enzymes of endogenous uric acid formation

 (1) protein degradation in human cells and other nucleic acid metabolism of purine compounds by the action of some enzymes of endogenous uric acid formation.

(2) purine content in the food compounds, nucleic acids and nucleoprotein components, after digestion and absorption, the role of some enzymes generated by exogenous acid.

uric acid formation is a complex process that requires the participation of some enzymes. These enzymes can be divided into two categories: promotion of uric acid synthesis of the enzyme, mainly 5 - phosphate DNA -1-- pyrophosphate synthase, adenine nucleotide phosphate transferase, phosphoribosyl pyrophosphate amide transferase and xanthine oxidase ; inhibition of uric acid synthesis enzyme, is mainly hypoxanthine - guanine nucleotide transferase. Gout is caused due to various factors that abnormal activity of these enzymes, such as promoting increased uric acid synthase activity, inhibition of uric acid synthase activity die down, resulting in excessive production of uric acid. Or as a result of various factors leading to occurrence of renal row of urinary acid obstacles to the accumulation of uric acid in the blood, resulting in hyperuricemia.

gout will have kidney damage, mainly because it can cause chronic interstitial nephritis and renal uric acid stone formation. the general if we can come down uric acid, then the damage to the kidneys will drop down at the same time will alleviate the symptoms.

gout should be on prevention. In order to prevent and treat gout, the diet should be less than three three:

1 more water and less soup. High serum uric acid and gout patients should drink plenty of water, drink less broth, soup, chicken soup, hot pot soup. Osmotic pressure boiled water dissolve the body most conducive to a variety of harmful substances. To drink boiled water to dilute the uric acid,cheap UGG boots, speed up the metabolism so that uric acid levels. Soup contains large amounts of purine components, not only can not dilute the uric acid after drinking, but lead to increased uric acid.

2 more alkaline food and less acidic foods. Patients with gout purine metabolic disorder itself, uric acid, if too much to eat acidic food, will be worse, is not conducive to recovery. The more alkaline food to help supplement of potassium, sodium and chloride ions to maintain acid-base balance,Discount UGG boots, as in patients with endocrine disorders, an alkaline substance is not easy to absorb. Proposed soda drink containing minerals, trace minerals in only a small amount of absorption under the action for the benefit of improving the patient's body acidic environment.

3 eat more vegetables and less to eat. More eating, helps to reduce purine intake, increased vitamin C, increased cellulose. Eat less conducive to control calorie intake, limiting weight, lipid-lowering diet.

1, the principles and objectives of the treatment of gout treat gout

principle is: a reasonable diet; sufficient water intake; regular living system; appropriate physical activities; effective drug treatment ; regular health checks.

clinical treatment of gout usually required to achieve the following objectives:

(1) as soon as possible termination of acute arthritis;

(2) to prevent the recurrence of arthritis;


the water and refrain from smoking, adhere to proper physical exercise, weight control to avoid obesity, potassium, sodium, calcium, magnesium and other minerals more food, in the body often has the final metabolite alkaline sex. Eat more vegetables, fruits, nuts, soy and mushrooms, milk and other basic food. Alkaline food: tea, cabbage, persimmon, cucumber, carrots,UGG boots cheap, spinach, cabbage, lettuce, taro, seaweed, citrus, figs, watermelon, grapes, raisins, chestnut, coffee, wine.

3, acute attack of gouty arthritis treatment of acute attack of gout

timely treatment, mainly to control symptoms, the most effective drugs: colchicine, other drugs also anti-inflammatory pain, inflammatory pain Xikang, ibuprofen and so on. Quick the colchicine, but the side effects is also the largest. Medicine are: wine Qingbi meridians.

4, chronic treatment of gouty arthritis gouty arthritis

soon develop into a chronic it is difficult to restore. Mainly to avoid a recurring injury in the kidney and joint function, the greater of gout stones can be surgically removed.

5, intermittent attacks of gout treatment

intermittent episodes of treatment is mainly to maintain normal uric acid (6.5 mg / dl), protection of renal function and prevent gouty nephropathy. In addition to adhere to this general treatment, it is best to use to promote uric acid excretion and uric acid synthesis inhibiting drugs. Inhibition of synthesis of uric acid in clinical drug only allopurinol, and promote the formation of uric acid Shu Huang C drugs, gout and other benefits cents. Medicine are: compound Shenjin capsules.

6, the treatment of gout

Late Late has formed the majority of patients with gout gouty nephropathy gouty nephropathy with advanced high uric acid symptoms should be actively controlled, so that long-term maintenance of normal levels of uric acid, protect the kidneys,UGGs, preventing the development of uric acid nephropathy. Eliminate all factors that affect kidney function. To prevent urinary tract infections, hypertension, diabetes and the incidence of atherosclerosis.

reminder: Although gout is a lifelong disease, but as long as appropriate treatment, disease control is good, do not have any complications, there would be no threat to life.

induced arthritis, acute gout of the six factors:

fatigue: 45.7%

diet transferred (into the high-purine diet): 43.2%

excessive drinking: 25.9%

cold cold: 18.5%

joint trauma: 15.5%

excessive exercise: 9.6%